Adhatoda vasica belonging to Acanthaceae family, commonly known as Adosa, Adhatoda vasica Flowers, Antibacterial activity, Antifungal activity, Diffusion. Abstract. The present study aimed to evaluate the in vitro antimicrobial activity of pharmacologically important Adhatoda vasica plant extracts. Antibacterial activity of leaf extract of Adhatoda vasica was studied against Bacillus subtilis, Antibacterial activity was determined by disc diffusion method.

Author: Meztilmaran Kilkis
Country: Rwanda
Language: English (Spanish)
Genre: Environment
Published (Last): 10 April 2011
Pages: 117
PDF File Size: 7.76 Mb
ePub File Size: 11.35 Mb
ISBN: 288-1-44352-487-4
Downloads: 32629
Price: Free* [*Free Regsitration Required]
Uploader: Zulkilrajas

In the present communication we report the antimicrobial, antioxidant, and anticancer effects of Vasicine acetate acetylated from Vasicine obtained from A.

In vitro antibacterial activity of selected medicinal plants from lower Himalayas.

Zones of inhibition were recorded in millimetres and the experiment was repeated twice. Table 4 Cytotoxic effect of Vasicine acetate against A lung adenocarcinoma cancer cell line. Support Center Support Center. Evaluation of antioxidant activity of isoferulic acid in vitro. Vasicine acetate was obtained antibacteriap acetylation of Vasicine. HPLC chromatograms of the ethanol extract of the leaves of Adhatoda vasica. The structure of the isolated compound Vasicine and Vasicine acetate Figure 1.


Open in a separate window. The combined chloroform extract was washed with water, dipped, and dried over anhydrous sodium sulphate. Sample ethanol extract Vasicine acetate showed moderate antibacterial activity compared to Vasicine. The mobile phase was filtered through a 0.

Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

It is inferred that methanolic crude extracts of the above mentioned plantsexhibitantibacterial activities against pathogenic bacteria, which proved the ethnobotanical importance of the selected plants that indigenous vasixa use for cure against various diseases.

Author information Article notes Copyright and License information Disclaimer. Vasicine acetate showed antimycobacterial activity [ 15 ].

B revised New Delhi, India: The solutions were filtered through a membrane filter pore size 0. Glossary of Indian Medicinal Plants. The present studies cover antibacterial activity of the crude methanolic extracts of 11 medicinal plants viz.

Antibacterial Activity of Leaf Extracts of Adhatoda vasica – MAHE Digital Repository

The fraction was further purified and the compound Vasicine was isolated. Please review our privacy policy. The worldwide threat of antimicrobial resistance.

Vasicine is reported to have bronchodilatory, respiratory stimulant, and uterine stimulant effects [ 14 ]. The emergence of drug-resistant pathogens and the activoty in diseases affecting the immune system have greatly intensified the need to investigate new bioactive metabolites for potential pharmaceutical and industrial applications [ 12 ].


Antibacterial activity of adhatoda vasica leaf extract

Cytotoxicity of each sample was expressed as IC 50 value. It was then distilled on a water bath and the residue was washed with little n-hexane. Essential oils of the leaves of A.

The radical scavenging activity of Vasicine acetate at different concentrations is shown in Table 3. Vasicine showed antimicrobial activity against S. Structure of the compounds: Results and Discussion The ethanol extract of A. Antimicrobial and antimycobacterial activities of methyl caffeate isolated from Solanum torvum Swartz. The leaves are used to treat malarial fever, chronic fever, intrinsic hemorrhage, cough, asthma, leprosy, skin diseases, antibacterixl piles [ 6 ].

The extract was filtered through Whatman No.