Fundamental principles of bhaishajya kalpana. The word Bhaishajya Kalpana is composed of two words – Bhaishajya and Kalpana. The word. Bhaishjya kalpana deals with the Basic Ayurvedic pharmaceutics. •The first systematic knowledge of Bhaishajya Kalpana is found in Caraka. Doctor of Medicine in Rasashastra & Bhaishajya Kalpana (Medicinal Chemistry and Pharmacy) is Non – Clinical course. Keeping with tradition, the course.

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It is certainly possible that the quality of the adjuvant and other ingredients may influence the expression of biological activity. But not all the parts of the substance are always therapeutically useful in view of the specific diseased state. In such cases two parts of water is added to the ground plant material and it is left to soak overnight.

Avaleha – it is a semi-solid preparation of the drugs bhaisahjya for licking. Both function as weak wines but rich and fortified with active principles Ramachandra Rao, This indicates drug preparation and processing methods can influence expression of pharmacological activity. Creams, ointments, lotions, dusting powders etc.

The criterion to determine the final stage of the formulation before making pills is that it should not stick to the fingers when rolled. Influence of source of adjuvant or vehicle on the expression of pharmacological activity Many a times the place or source of materials especially of adjuvants and vehicles is not specified.

In Ayurvedic Formulary of India which can be considered as an authentic source book- twenty one type of drug formulations nhaishajya been mentioned.

This process ensures absorption of the active aklpana properties of the ingredients used, into the oil base. The water insoluble plant material is separated and thrown out as a waste material at the end of all these extraction processes. Such processing is termed as pharmaceutics i.


Dissertation submitted to Gujarat Ayurved University, Jamnagar. The plant ingredients are dried and made into fine powders, separately kalpaan ground to soft pastes before they are rolled in to pills with the help of fingers.


The medicated oil generally will have the colour, odor and taste of the ingredients used. The above illustrations are just few examples of a vast array of factors that may influence expression of pharmacological activity.

Bhaishajya Kalpanaa – The Ayurvedic Pharmaceutics – An Overview

They are purified by boiling the raw material with different liquid materials till a soft mass is obtained and repeatedly processed to obtain its purified form known as sodhita guggulu. The results obtained indicate in many cases adjuvant used may not be inert but per se may produce significant pharmacological activities. Then it is strained through cloth and the solid matter is allowed to settle.

Open in a separate window. Severity of the disease invites use of concentrated drug forms. The retained liquid after boiling is then filtered through a muslin cloth. Powder of each drug is weighed separately and mixed thoroughly.

Aasava or Aristas – these are fermented preparations of medicinal plants. Different aspects of their preparation and use have been discussed. They are preserved in glass, polythene or aluminum containers. This tool needs to be handled judiciously, if not done bhashajya it is likely to prove injurious or sometimes fatal to the life of the patient who is receiving it. The form which ultimately comes into use by the patient is termed as a drug delivery system or drug dosage form.

This can be achieved through specific processing. Hence while making changes in the classical formulation this point should be noted and changes should not be made without valid reasons.

Administration of cyclophosphamide caused significant suppression in anti-body formation. Groups of classics known as Greater triad Brihat tr a yee and Lesser triad Laghu trayee are noteworthy among them.

Bhaishajya Kalpanaa – The Ayurvedic Pharmaceutics – An Overview

Comparative Pharmaco-clinical study on Panchtikta ghrita prepared by different methods in Ekakustha Psoriasis M. Sattva – is the water extractable solid substance collected from a plant.

Not all but some of the plant ingredients are therapeutically active. If required liquids like milk, ghee butter oiloil, cow urine in the measure of 10 ml. Per-urethral, per-vaginal administration of medicated oils and emulsions. The paste is then rolled into a bolus which is wrapped in the coverings of leaves. Parameshvara Charitable trust; When the mass is properly ground and is in a condition to be made into pills- flavoring agents are added and ground again.


It is then removed from the hearth and allowed to cool. This facilitates the extraction of the active principles contained in the drugs.

But four, eight and sixteen parts of water is added to soft, hard and very hard plant material respectively bbhaishajya the decoction to be used as base material for preparation of medicated oil or ghee. In all these extraction methods water soluble active ingredients of the plant are extracted.

Asafoetida and salt may also be roasted, powdered and then added. When more than one liquid is mentioned for grinding, they are used in succession. They are put to use depending upon the condition of the patient with respect to his digestive capability e. Ayurvedic pharmaceutics is not an exception to this.

A combined solvent system is also used sometimes. Due to space constraint it is not possible to give full description of all these forms. Influence of drug processing during preparation A study carried out by Rajesh Barvaliya on A-Panc a tikta ghrita literally translates as medicated ghee prepared from five drugs having bitter taste principles containing ghee involved buaishajya of the formulation by three methods and subjecting them to bjaishajya study.

Table 1 Shelf life of different types of drug forms. The ratio of the ingredients, unless specified otherwise, is oil four part, kalka- one part and liquid sixteen parts however, there are several jalpana.